Condensin I folds the Caenorhabditis elegansgenome Chromosomes require extensive folding to fit DNA molecules orders of magnitude longer than the diameter of nuclei. This is achieved by the formation of loops by Structural Maintenance of Chromosomes complexes. In a study of the Meister group, they found that in contrast to mammals in which cohesin creates these loops, condensin I in C. elegans is the major long-range loop extruder…..
New Research Paper in EMBO Journal... from our Ambizione fellow Gaëlle Lentini elucidating the mechanism of cellular abscission in Toxoplasma gondii. They identified a set of five proteins crucial for the buildup of the plasma membrane at the division plane, ensuring the successful completion of cytokinesis.
Expansion of metabolically labelled endocytic organelles and cytoskeletal cell structures in Giardia lamblia using optimised U- ExM protocols A collaboration between the Faso and Ochsenreiter labs from the IZB now published in Microbial Cell. Congratulations to the three PhD students, Clirim Jetishi, Erina Balmer and Bianca Berger who spearheaded this project and present an ..."optimised, shortened, and modular protocol that can be swiftly adjusted to the investigators needs in this important protozoan model organism”.
Faso Group: Nourseothricin as a novel drug for selection of transgenic Giardia lamblia Nourseothricin expands the limited molecular toolbox for this species of global medical importance. It can be used as a selection marker and it is compatible with both neomycin and puromycin to select for dual transfection events.
