Institute of Cell Biology


Prof. Dr. Eduardo Moreno

Cell Fitness: Genetic and Molecular studies

Humans are able to detect fitness decay in colleagues by looking at the graying of the hair or the wrinkles in their faces. Work from my laboratory in the last few years has shown that cells can also detect fitness levels of neighboring cells using a molecular code. Those "fitness fingerprints" (Rhiner et al., Dev.Cell, 2010; Merino et al., Curr. Biol., 2013) can be used to mediate cell selection by recognizing and eliminating less fit cells during ageing (Merino et al., Cell, 2015), regeneration (Moreno et al., Curr. Biol., 2015) and cancer (Levayer et al., Nature 2015).

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  • 2014: ERC Consolidator Grant Award
  • 2012: ERC Proof of Concept Award
  • 2011: Josef Steiner Cancer Research Award
  • 2007: ERC Young Investigator Award
  • 2002: CBM-UAM PIMP prize
  • 2002: Brupbacher Foundation Young Investigator Prize, Zurich
  • 1999: Extraordinary Prize for the best thesis Universidad Autónoma Madrid
  • 1999: Innogenetics-SEBBM Young Scientists Prize