Prof.Dr. Carmen Faso

Mechanisms of unconventional protein secretion

In our group, we study mechanisms of unconventional protein secretion and develop translational approaches in the context of parasite-host interactions. Our model organisms are two intestinal parasitic protists called Giardia lamblia and Entamoeba histolytica.

Please scroll through current projects on the research tab for more information.

For information on my engagement with the Multidisciplinary Center for Infectious Diseases of the University of Bern, please follow this link

Group Faso

Staff Scientists

Technicians

PhD students

Master students

Publication Year Type

Dr. Shweta V. Pipaliya

Dr. Zahra Rezaei

Tim Schärer

Research

UPS in parasitic protists

Balmer and Faso, 2021

Unconventional protein secretion (UPS), proteins crossing the plasma membrane outside the canonical secretion pathway, is a topic that has been of growing interest of cell biologists in various study systems. UPS was shown to be at the core of health and disease related processes and a better understanding of the involved molecular mechanisms holds great promises for translational applications. We are studying UPS in the protist parasite Giardia lamblia, with a streamlined endomembrane system, to advance the understanding of UPS mechanisms in eukaryotes.

see here for a recent review
Funding sources: SNSF

Alpha-giardins in UPS